The A22 at the Cophall roundabout at Polegate was closed in both directions following a serious collision yesterday.
Emergency services responded after the collision involving two motorcycles at about 3.30pm.
Police said: “We thank motorists for their patience while officers responded to this incident.
We are appealing for anyone who saw what happened or anyone with relevant dashcam footage to come forward.
Please report on the Sussex Police website or email: email@example.com and quote Operation Tavistock.”